🐾 PawSafe Check

Is Benadryl (diphenhydramine) Toxic to Pets?

Yes — benadryl (diphenhydramine) is mildly toxic to cats. Yes — benadryl (diphenhydramine) is mildly toxic to dogs.

CatsMildly toxicIs benadryl (diphenhydramine) toxic to cats? →DogsMildly toxicIs benadryl (diphenhydramine) toxic to dogs? →

PawSafe Check is for general information only and is not veterinary advice. Always contact your veterinarian or a poison control service if you think your pet has been exposed.

Toxic compound
Diphenhydramine
Toxic parts
Tablets, liquids, combo products
Also known as
benadryl

Symptoms

Cats (mildly toxic)

  • Sedation or agitation
  • Dry mouth
  • Fast heart rate
  • Vomiting

Dogs (mildly toxic)

  • Sedation or agitation
  • Dry mouth
  • Fast heart rate
  • Vomiting

What to do

If your cat ate benadryl (diphenhydramine)

  • Remove any plant material from your cat's mouth and keep it out of reach.
  • Gently rinse the mouth and offer fresh water.
  • Call your vet if symptoms persist, get worse, or your cat is small, young or elderly.

If your dog ate benadryl (diphenhydramine)

  • Remove any plant material from your dog's mouth and keep it out of reach.
  • Gently rinse the mouth and offer fresh water.
  • Call your vet if symptoms persist, get worse, or your dog is small, young or elderly.

Good to know

Vets sometimes recommend diphenhydramine at specific doses, but overdoses cause agitation or sedation and a fast heart rate. Some products also contain decongestants, which are dangerous.

Is your pet covered for emergency vet bills?

Compare pet insurance quotes →

Frequently asked questions

Is benadryl (diphenhydramine) toxic to cats?

Yes — benadryl (diphenhydramine) is mildly toxic to cats. Common signs include sedation or agitation, dry mouth, fast heart rate.

Is benadryl (diphenhydramine) toxic to dogs?

Yes — benadryl (diphenhydramine) is mildly toxic to dogs. Common signs include sedation or agitation, dry mouth, fast heart rate.

Which parts of benadryl (diphenhydramine) are toxic?

Tablets, liquids, combo products.

What makes benadryl (diphenhydramine) toxic?

Diphenhydramine.

Related guides

Related items

Free printable: 25 pet-safe houseplants + emergency numbers

We only use your email to send the list and occasional pet-safety tips. Unsubscribe anytime. Privacy policy